Stage IIB Ovarian Management
- Develop the management plan (pharmacological and nonpharmacological).,
- Discuss the appropriate diagnostic testing for the patient,
- Discuss differential diagnoses with ICD 10 numbers for each.,
- Base on the International Federation of Gynecology and Obstetrics (FIGO) give treatment examples for a patient with a Stage IIB Ovarian Cancer.
Management Plan for Stage IIB Ovarian Cancer
Pharmacological Management
Chemotherapy
- First-line: Carboplatin + Paclitaxel (Standard regimen)
- Alternative: Cisplatin + Paclitaxel (For patients intolerant to carboplatin)
- Neoadjuvant or adjuvant chemotherapy based on surgical outcomes
Targeted Therapy
- Bevacizumab (Avastin): Angiogenesis inhibitor for advanced cases
- PARP Inhibitors (Olaparib, Niraparib, Rucaparib): Used in patients with BRCA mutations
Pain and Symptom Management
- Analgesics (Acetaminophen, NSAIDs, Opioids if necessary)
- Antiemetics (Ondansetron, Metoclopramide) for chemotherapy-induced nausea
- Hormonal therapy (GnRH agonists) if indicated
Nonpharmacological Management
- Surgical Intervention:
- Cytoreductive surgery (debulking) to remove visible tumors…
Management Plan for Stage IIB Ovarian Cancer
Pharmacological Management
Chemotherapy
- First-line: Carboplatin + Paclitaxel (Standard regimen)
- Alternative: Cisplatin + Paclitaxel (For patients intolerant to carboplatin)
- Neoadjuvant or adjuvant chemotherapy based on surgical outcomes
Targeted Therapy
- Bevacizumab (Avastin): Angiogenesis inhibitor for advanced cases
- PARP Inhibitors (Olaparib, Niraparib, Rucaparib): Used in patients with BRCA mutations
Pain and Symptom Management
- Analgesics (Acetaminophen, NSAIDs, Opioids if necessary)
- Antiemetics (Ondansetron, Metoclopramide) for chemotherapy-induced nausea
- Hormonal therapy (GnRH agonists) if indicated
Nonpharmacological Management
- Surgical Intervention:
- Cytoreductive surgery (debulking) to remove visible tumors…
Management Plan for Stage IIB Ovarian Cancer
Pharmacological Management
Chemotherapy
- First-line: Carboplatin + Paclitaxel (Standard regimen)
- Alternative: Cisplatin + Paclitaxel (For patients intolerant to carboplatin)
- Neoadjuvant or adjuvant chemotherapy based on surgical outcomes
Targeted Therapy
- Bevacizumab (Avastin): Angiogenesis inhibitor for advanced cases
- PARP Inhibitors (Olaparib, Niraparib, Rucaparib): Used in patients with BRCA mutations
Pain and Symptom Management
- Analgesics (Acetaminophen, NSAIDs, Opioids if necessary)
- Antiemetics (Ondansetron, Metoclopramide) for chemotherapy-induced nausea
- Hormonal therapy (GnRH agonists) if indicated
Nonpharmacological Management
- Surgical Intervention:
- Cytoreductive surgery (debulking) to remove visible tumors…
Management Plan for Stage IIB Ovarian Cancer
Pharmacological Management
Chemotherapy
- First-line: Carboplatin + Paclitaxel (Standard regimen)
- Alternative: Cisplatin + Paclitaxel (For patients intolerant to carboplatin)
- Neoadjuvant or adjuvant chemotherapy based on surgical outcomes
Targeted Therapy
- Bevacizumab (Avastin): Angiogenesis inhibitor for advanced cases
- PARP Inhibitors (Olaparib, Niraparib, Rucaparib): Used in patients with BRCA mutations
Pain and Symptom Management
- Analgesics (Acetaminophen, NSAIDs, Opioids if necessary)
- Antiemetics (Ondansetron, Metoclopramide) for chemotherapy-induced nausea
- Hormonal therapy (GnRH agonists) if indicated
Nonpharmacological Management
- Surgical Intervention:
- Cytoreductive surgery (debulking) to remove visible tumors…
